After the latest update, Wulfrum slimes and drones are still very common at the very start of the game. While the frequency of their spawning isn't necessarily the problem, they're just way too powerful (+6X HP compared to slimes in that area and they hit hard) -- and drones move very quickly for starting mobs, and nearly impossible to run from at default walking speed. Without any real way to defend against them, these mobs can be downright annoying right at the start.
I propose one of two solutions. Since their loot/gear isn't very good as it is, it may be best to weaken them significantly, and slow down drones. Or alternatively, keep their stats the same, but don't allow them to spawn until post-EoC. This will make them very suitable difficulty-wise, although you'll also have to buff the loot they drop in order to give them any purpose at that point in the game.
Personally I'd prefer holding them off until after a boss.