Use a Daedalus Stormbow with Holy Arrows for the Destroyer and Twins. Switch to Ichor arrows and then spam Onyx Blaster with Crystal bullets for Prime. As for armor, your best choices are Titanium and Palladium, with the Squire's Great Helm becoming available after one mech (you'll have to go out of your way to get it, but the helmet alone provides about as much regen as a full set of crimson armor.)