PC How to activate a script in-game?

Nomad000

Skeletron Prime
I saw someone make a script for automated fishing, but I have no idea how to put or activate this in the game, the hotkey is F2, but how do I make this work?
 
Terraria doesn't have any scripting support built in, so they must have been using some kind external program. Was is AutoHotkey, perhaps?
 
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