I'm Having an issue where the tweaks folder is empty, even though a tweak list has been created. I've tried uninstalling the program, but nothing seems to be working. I also looked in the logs, and saw that there were multiple errors when trying to create a tweak list. also something about "terrariatweakerwashere" missing or something. Please help in anyway you can.
At any rate, however, please start a a conversation with me (using the forums Conversations feature) so you can share logging information and more details.
I've identified an issue very similar to what you described (probably the same issue), which will be fixed very soon in a hotfix.