Can confirm what Ranoru experienced. I tried opening a biome chest early without the key (and before Plantera) and not only did the chest NOT open (can that be fixed too, so they can open before Plantera?) but I lost everything in my inventory except a couple things. I quickly alt-F4'd and luckily the last autosave interval was just before that point so I was able to get my stuff back. Others might not be so lucky...
Also, is it possible to add a go-to-mouse function on a keypress? Basically Rod of Discord on command. I often use GTM tweaks because it just makes getting around so much more convenient, and you can make floating bases/houses without needing to compromise with teleport pads, or rope, or having to build it on the ground for enemies can get in etc.