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It only affects other piercing attacks., so the bullets wouldn't be affected unless piercing ammo was used. The cannonballs are shot more slowly, so it can be assumed that their fire rate would be low enough for their damage output to not suffer.
I think that he entered the dungeon when he was young in order to look for things to sell, and accidentally awakened Skeletron and the skeletons; resulting in the former cursing him and using him in order to dissuade would-be intruders.
Since Skeletron's orders were simple, the Clothier actually...
I'm surprised nobody mentioned the Tin Shortsword and Pick. Both of them are marginal upgrades over their Copper counterparts, but you have to craft a Furnace and gather the ore before you can actually use them. On top of that, the pick is still inferior to the Cactus Pick.
Another case is the...
Making it a regen would be the simplest way, and could actually be applied to every mode, and not just Master. For instance, it could be 5% of the Player's maximum health over 30 seconds (The extra 10 seconds would let the Player take some damage while regenerating).