If you really feel like it, to get the achievement for 200 fishing quests you can make biome fishing farms.
@HappyDays made a
really useful tutorial on this.
Make a tunnel underground from edge to edge of the world, alternatively make a minecart rail spanning the whole map. Saves a lot of time.
Make a huge boss arena with heart statues and stuff for the later boss fights.
Make an area with mud ready for a chlorophyte farm.
Make the dungeon more suitable to grind in (flat areas etc.)
Contain the corruption (5 block wide wall all around it) to stop the jungle being corrupted (I hate that too you know
)
Make places for banners, statues and trophies, try to collect every one
(You can see my
banner thingy here that has all of the banners in the game
)
As
@Myth said, make more rooms for npcs, make a plant farm...
Also, try to make a surface glowing mushroom biome farm ready for the truffle; it's best to start farming glowing mushrooms early.
As an alternative to more rooms, if you have the time make separate themed houses for each npc e.g. a blacksmith for the merchant, a small hospital for the nurse (makes the whole thing more enjoyable, also gives you something to brag about on the forums
That's a long wall of text I know
If you get these things done you will be happy