FlakMaster
The Destroyer
These systems are clunky for the UI.
It can be made not to be. The same issue has been brought up in my Dyes thread, but there's a lot of things you can do with the GUI.
Besides, the 'Potion Bar Upgrade Items' are very much like the 'Starmap Upgrades' from Starbound (they removed it), and both of them are examples of bad sandbox game design.
It breaks immersion and it is counterintuitive. Why would it work only once? Why does it not stack? Why does similar items stack? Those are the questions a new player will ask.
Firstly, I've never played Starbound so I'll get that out of the way.
Secondly, from a new player's perspective I get what you're saying. Hence why almost no one wants this for the normal difficulty. I've already accepted that fact. But for expert mode, the majority will be playing it with experience.
Limiting potions like this is precisely how you are limited by accessories.
Also I must frown upon the OP for using unscientific methods of obtaining buffs. Is it practical to gather ALL these buffs? Will people actually seek out ALL these buffs or use just enough to kill the boss or run events?
Concerning the Moon events, it's not necessarily about completing it. It is moreso trying to get as far as possible. This is even greater so because of the fact that the moon events are end-game. Because of that, you'd want the most optimal set-up. Though I will admit, I did go slightly overboard.