Yvori
Terrarian
Ah? The hotkey is designed to consume items, you mean?Sadly, it is hard to impossible to make Horn o' Plenty work on heal hotkey as it is designed so that the item gets consumed on activation
Because lots of mods (Infinity, QWERTY's Mod, and Peculiarity to name just a few) add potions that don't get consumed when used, even when used with the hotkey.
Could contact one of the authors of those and see how they did it, if that's an issue.